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This is the one that creates dihydrotestosterone (DHT), the “male estrogen”, which is strongly associated with the development of prostate enlargement (benign prostatic hyperplasia) and prostate cancer.

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Also added that the patients who received dose-dense chemotherapy had better overall survival (OS) and disease-free survival than those on the conventional schedule; a statistically significant OS benefit was observed in patients with estrogen receptor (ER)-negative tumors but not in those with ER-positive breast cancer.

As is the case with many nutritional intervention studies, controlled trials examining the efficacy of vitamin D supplementation for AD have reported mixed results.

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